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In 1975 two mothers living in Old Lyme, on the east side of the Connecticut River, whose children had fallen ill with fever, aches and swollen joints, independently refused to accept a vague diagnosis of juvenile rheumatoid arthritis from the doctors and began contacting other mothers in the area. In one street one mother found four children with similar symptoms. Convinced that the disease must be caused by an infective agent, they contacted health officials and asked them to investigate.
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