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About 200 cases of Creutzfeldt-Jakob disease are recorded annually in the United States, according to the National Institutes of Health. In fewer than 1 percent of cases, the disease is transmitted by exposure to brain or nervous system tissue, and there have been only four reported cases of transmission via surgical instruments. None of those were in the United States, and the most recent case was in 1976, Pepe said earlier this month.
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